Scott D. Solomon, MD is the Edward D. Frohlich Distinguished Chair, Professor of Medicine at Harvard Medical School and directs the Clinical Trials Outcomes Center at Brigham and Women’s Hospital. His research interests have focused on changes in cardiac structure and function following myocardial injury and heart failure, and modifiers of risk and influences of outcome in heart failure, and innovations in clinical trials in cardiovascular medicine. He has led numerous phase 2 and phase 3 clinical trials in heart failure and related diseases, including many trials in heart failure with mildly reduced and preserved ejection fraction. He serves as Editor for Braunwald’s Heart Disease.