Cellenion and Thermo Fisher Scientific Announce Partnership for Single Cell Mass Spectrometry-Based Proteomics Analysis

Cellenion, a BICO company, announced today a co-marketing agreement with Thermo Fisher Scientific to advance single cell proteomics analyses. The goal of the partnership is to combine Cellenion’s cellenONE® and proteoCHIP^TM with Thermo Fisher’s TMT multiplexing technologies and Thermo Scientific™ Orbitrap™ mass spectrometers to deliver complete solutions, from single cell isolation and automated sample preparation through to mass spectrometry (MS)-based proteomics analysis on single cells.

Cellenion has developed cellenONE®, a system combining image-based single cell isolation and nanoliter dispensing to perform every step of the sample preparation using a single device, and proteoCHIP 12*16, a dedicated consumable for automated and loss-less sample preparation prior to multiplexed single cell proteomics analyses.

Thermo Scientific Orbitrap mass spectrometers in combination with enhanced sensitivity and throughput by multiplexing cells with TMT isobaric labelling allows their platforms to deliver more proteins per cell and from tens to hundreds of cells per day, going beyond one cell at a time.

With single cell proteomics providing vital information on the state of individual cells within heterogeneous environments, the combination of this sample preparation technology with Thermo Fisher’s TMT multiplexing technologies and Orbitrap mass spectrometers will provide researchers with powerful tools to standardize MS-based single cell proteomics workflows.

“This partnership will accelerate development of novel solutions for sample preparation prior to multiplexed single cell proteomics analyses,” explained Dr. Guilhem Tourniaire, Managing Director at Cellenion. “By automating sample preparation, we hope to encourage the adoption of these revolutionary methods, bring a new dimension to Biology, and ultimately, contribute to the future of health.”

“Single cell proteomics has the potential to disrupt many areas of biology through granular and precise research. We know our customers want to do single cell proteomics because they are on a mission to advance human health,” said Daniel Lopez Ferrer, Director of the Proteomics Program at Thermo Fisher. “They know that to perform single cell analysis at scale our mass spectrometers in combination with TMT multiplexing is the way to go. Partnering with Cellenion enables us to deliver researchers a convenient full end to end solution to perform single cell proteomics analysis that will accelerate their progress mastering the complexities of biology”.

For more information about Cellenion’s single cell mass spectrometry-based proteomics offering, please visit: www.cellenion.com/applications/single-cell-proteomics/